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By Michelle Scott, Kate Murray and Sylvy Bouchard

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Sebaceous Adenitis
(Standard)

Sebaceous Adenitis (SA) is a skin disease of young, adult dogs in which the sebaceous glands become inflamed and may eventually be completely destroyed. SA is seen in about a dozen breeds, and is especially prevalent in Standard Poodles and Akitas.
In the Standard Poodle, the disease is characterized by hair loss/thinning, silver scales that adhere tightly to the hair, and in severe cases, secondary skin infection causing a musty aroma. A subclinical form of the disease is only detectable by microscopic examination of a plug of skin. Dogs that are subclinically affected look normal. Documented cases of subclinically affected dogs becoming clinically affected may mean that the subclinical form is an early stage of the disease.
SA can be diagnosed by a simple punch skin biopsy only. Antibiotics may help secondary skin infections, but other attempts to "cure" SA-affected dogs have provided only temporary improvement. Some breeds respond to Accutane. Standard Poodles do not.
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